Parametric modeling of protein–DNA binding kinetics: A discrete event based simulation approach

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Parametric modeling of protein-DNA binding kinetics: A discrete event based simulation approach

To understand the stochastic behavior of biological systems, we adopt an “in silico” stochastic event based simulation methodology that can determine the temporal dynamics of different molecules. The main requirement for this technique is the event execution time models for the different biological functions of the system. This paper presents a parametric model to determine the execution time o...

متن کامل

Reduction of production disturbances of a shoemaking industry through a discrete event simulation approach

This study presents a reduction of production disturbances of a shoemaking industry through discrete event simulation approach. The study is conducted at Peacock Shoe factory found in Addis Ababa, Ethiopia.  This factory faces line balancing problem that becomes production disturbance for its assembly lines. Detail time study is carried out for the selected shoe model using stopwatch. Assembly ...

متن کامل

A JAVA-BASED FRAMEWORK FOR DISCRETE EVENT SIMULATION A framework for Discrete Event Simulation and MOdeling

The system presented bridges the gap between three different research areas: discrete event simulation, heuristic optimization methods and distributed systems technology. Its goal is to provide a framework which supports an efficient implementation of simulation optimization projects, including heuristic optimum seeking procedures and parallel execution of experiments. It is written completely ...

متن کامل

Peg: Formalizing Lp-based Modeling of Parallel Discrete-event Simulation

Logical process (LPs) is a widely used modeling paradigm in parallel discrete-event simulation (PDES). However, there is a lack of effective methods for formalizing the LP-based modeling of PDES. This situation obstructs the unambiguous and platform-independent description of the LP-based model. To solve this problem, in this work, a formalism named Partitioned Event Graph (PEG) is presented. P...

متن کامل

1999: Knowledge-based Modeling of Discrete-event Simulation Systems

Modeling a simulation system requires a great deal of customization. At first sight no system seems to resemble exactly another system and every time a new model has to be designed the modeler has to start from scratch. The present simulation languages provide the modeler with powerful tools that greatly facilitate building models (modules for arrivals or servers, etc.). Yet, also with these to...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Discrete Applied Mathematics

سال: 2009

ISSN: 0166-218X

DOI: 10.1016/j.dam.2008.06.046